I said I wasn't going to do this but I can't stop myself. I'm only doing it because I know there are only a few people looking at this blog (hello to you!).
I started the submission process last week. I've spent lots of time researching agents and whittled it down to my top 50. Last Monday, I sent queries to the top 10, with a plan to send 10 a week, giving me a chance to amend my query, synopsis, etc. if I needed to.
Within 3 days, I had three rejections (1 personal, 2 form), 1 partial request (from one of the 'uber-agents' I never expected to hear back from) and 1 full request!
I know it can all go terribly wrong from here. Up to now, the query process can be 'I don't like/rep your idea' which stings, but doesn't impugn your writing per se. But from the partial/full stage, it could be 'I liked your idea, but your execution...not so much.'
It's nice to have that little lift in thinking that maybe, just maybe, this could happen.